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Nobel Medicine 2025: Brunkow, Ramsdell, Sakaguchi Honoured

7 October 20251 min read
AWARDS & PERSONSNobel Medicine 2025:Brunkow, Ramsdell,Sakaguchi Honoured7 October 2025safalsetu.com

Why in the news

Three scientists shared the 2025 medicine Nobel for showing how immune cells are stopped from damaging the body.

Key facts

  • Regulatory T cells (Tregs) keep the immune system from attacking healthy tissue.
  • Relevance: autoimmune disease, cancer and transplants, plus new therapies.

Laureates

NameCountryRole
Mary E. BrunkowUSAInstitute for Systems Biology, Seattle; co-identified FOXP3
Fred RamsdellUSASonoma Biotherapeutics, San Francisco; genetics of immune regulation
Shimon SakaguchiJapanOsaka University; CD25+ Tregs

Exam angle

  • Match names with countries.
  • Key terms: Foxp3, peripheral tolerance.

Test yourself

1. The 2025 Nobel Prize in Physiology or Medicine was awarded for discoveries about which cells?

The prize recognised work on regulatory T cells and the Foxp3 gene.

2. Which 2025 medicine Nobel laureate, from Japan, discovered CD25+ regulatory T cells?

Shimon Sakaguchi of Osaka University discovered CD25+ regulatory T cells.

3. Which gene, linked with regulatory T cells, was central to the 2025 Nobel Prize in Physiology or Medicine?

The Nobel recognised work on regulatory T cells and the Foxp3 gene.

This topic is part of Daily Current Affairs 7 October 2025 (15 topics).

All topics of the dayDay quizOctober 2025

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